Companies We Have Invested In
Since 2004, Boston Harbor Angels have made investments in information technology, life sciences, consumer products, business products, services, specialty materials, aviation and more. Recent exits from investments include Medumo, Neuraly, and Siamab Therapeutics.
A|B’s product transforms a shopper’s Smartphone into a virtual shopping assistant & mobile self-checkout device to be used in a store’s aisles.
Aras Corp >>
Aras provides a suite of enterprise software solutions to coordinate the complicated business processes in engineering and production resulting in faster, more profitable product launches.
Blurr is a platform that allows users to effortlessly take, view and share every picture taken around them.
Solutions for individuals and small businesses to help them easily control how they appear in Google searches.
Automatically backs up your new and changed files.
Chromis Fiberoptics >>
Chromis is pioneering the use of high-performance plastic optical fibers to deliver data at the speed of light, filling needs for economical, high-bandwidth, short-distance data/video links in data center, professional audio/video, consumer electronics, and other high-performance computing applications.
Integrates off-the-shelf hardware and unique software inside a transparent engine in order to streamline development of complex systems such as network switches, satellites, or CT scanners, offering the first collaborative design and debug environment for Complex Field Programmable Gate Arrays (“CFPGAs” ).
GoodTwo helps you raise more money by rewarding your donors with targeted, limited-time offers from top-tier brands.
Gramify sells audio greetings featuring voices of famous celebrities/characters.
Cloud-optimized parallel database capable of performing high speed analytics on both structured and unstructured data.
Horizontal manages and delivers information for the built environment, making lifecycle data accessible and useful to all project members.
ImageRights International >>
ImageRights searches for unauthorized use of photos online.
Lessac Technologies >>
Producing near human quality expressive speech from plain text.
Mosaic Storage Systems
Mosaic provides a complete digital asset storage solution for professional and prosumer photographers.
Developer of communications systems infrastructure.
Oculis Labs has a pioneering software solution to display security – more effective, more efficient, and lower cost than current solutions.
Pawspot is a free pet supersite which allows pet owners to connect and share their love of natures’s greatest creatures, helping pet owners find and search for their animal companion’s needs no matter where they might live.
Fast growing internet advergaming platform that uses legal, fully US compliant poker and other games as content to sell advertising.
ReDigi creates the world’s first used digital marketplace with proprietary technology, uploads original, legitimately obtained digital media files without illegally copying them and removes all copies from the accessed computer and synced devices.
Regroup (formerly CollegeWikis) >>
Regroup provides you with a platform to communicate with your constituents, and for them to communicate with each other, while integrating with social media.
Scrible is a Google-integrated SaaS research and writing platform for school and work tackling the research and writing skills crisis in education today.
StylePath’s patented technology filters the web so shoppers can find clothing, jewelry, furniture and home decor that matches their unique taste.
“Googling” is standard practice. Vizibility delivers the first SearchMe Button for Google that instantly returns the search results people want first.
The world’s first multimodal mobile email.
Wasabi is a cloud storage company.
WebNotes is transforming the “post-search” space, making it easy to capture, organize, share, and present information found on the Web.
3Derm is a cost-effective skin imaging system that allows any user to take clinical-quality 3D images of concerning skin lesions and upload them instantly for review by a dermatologist.
Akston Biosciences >>
Akston Biosciences leverages its core expertise of designing novel fusion proteins to develop and manufacture new classes of biologic therapeutics for Type 1 diabetes (T1D) prevention, ultra-long acting insulin therapy, and vaccines.
Amsel Medical Corporation >>
Amsel Medical provides FDA Cleared surgical clamping technology, delivered minimally invasively through a fine 18G needle for targeted clamping of blood vessels and ducts >$1B market.
Anubis Bio >>
Anubis Bio is an animal health company committed to enhancing pet health using natural food products that support digestive health and normal intestinal function.
Astrocytes Pharmaceuticals >>
Astrocyte Pharmaceuticals Inc. is a small drug development company dedicated to clinically proving the neuroprotective benefits of selective astrocyte activation, and advancing breakthrough therapeutic agents for treating brain injury patients.
Avaxia Biologics >>
Avaxia is developing orally-delivered antibody therapeutics for diseases of the GI tract, using a proprietary antibody platform.
BIOARRAY Genetics is a molecular diagnostics company focused on changing the way in which cancer patients are evaluated and treated.
Biolectrics empowers people to improve health with innovative oral care. 65M US adults have periodontal disease (gum disease) and most do not receive treatment. Our OraFlow device treats periodontal disease at home using microcurrent stimulation.
Bliss Healthcare >>
Bliss Healthcare brings comprehensive premium healthcare to patients at home so families stay connected yet care for aging parents, loved ones.
Cambridge Endoscopic Devices
Revolutionizing least invasive surgery through a proprietary platform technology in endoscopic and laparoscopic instrumentation.
Develops and markets advanced medical devices that help healthcare professionals more effectively manage fluid management performance during arthroscopic surgery.
Chronix Biomedical >>
Applies proprietary techniques that utilize serum DNA to develop routine blood tests for the early detection and management of cancer.
Cognoptix is creating and developing a simple, innovative non-invasive eye scanning test for the early detection and diagnosis of Alzheimer’s Disease.
Corbus Pharmaceuticals >>
Corbus Pharmaceuticals is a clinical stage drug development company targeting rare, chronic, and serious inflammatory and fibrotic diseases with clear unmet needs.
CytoAgents is a privately held biotechnology company focused on the development of innovative pharmaceutical products for the treatment of COVID-19, Influenza and other viral infectious diseases.
Develops simple, accurate, and affordable products that deliver critical diagnostic information to clinicians and patients across the globe.
DeepLook is a patented, simple, point-and-click tool that integrates easily into mammography workstations, to fit seamlessly with the radiologist’s workflow.
Emovi is dedicated to providing the highest quality, most technologically advanced products for knee joint assessment to restore patient quality of life.
eSight is the perfect investment whereby angels can truly “do well by doing good”: restoring sight.
First Light Diagnostics >>
First Light Diagnostics develops innovative diagnostic tests that enable rapid and accurate detection of pathogens that can cause life-threatening infections.
GelMEDIX Inc. is an early-stage biotechnology company committed to innovating the next generation of ocular and regenerative therapies through its proprietary hydrogel platform.
Heads Up Health >>
The mission of Heads Up Health is to inspire and empower people to take control of their health and optimize their performance.
ImmuneXcite is a privately held biotech company based in Lexington, Mass., that is developing the next generation of immune-activating, anti-tumor biotherapeutics against a wide range of cancers.
Immusoft is developing a cutting edge approach to sustained delivery of protein therapeutics using a patient’s own cells.
Ionica Sciences >>
Ionica Sciences is a highly adaptable infectious disease diagnostics platform, focusing first on Lyme Disease (IonLyme Test), with rapid expansion to other vector borne diseases.
JBT is a clinical stage biopharmaceutical company developing a non-psychotropic synthetic derivative of THC.
Kalion Inc. >>
Kalion is an early stage industrial biotech company that will transform the traditional chemical industry by providing low-cost access to glucaric acid and S-3-hydroxybutyrolactone (3-HBL) using traditional, green, fermentation technology.
Landsdowne Labs is a Bob Langer, MIT spin out using advanced materials to address injury prevention.
Designs software that helps medical distributors and customers manage the supply chain of medical equipment.
Medumo helps healthcare organizations guide, track, and triage patients in the most intelligent, effortless way possible.
myBiometry is a platform to remotely monitor and manage patients with chronic conditions using software and biomarker data generated from proprietary sensors. Our initial focus is asthma.
Has developed a robotic brace that can play a significant role in stroke rehabilitation.
Neuraly is a biotech company founded by scientists and physicians with a worldwide reputation in the field of neurodegenerative diseases.
Creating and developing an innovative non-invasive and predictive laser eye scanning test for the early detection and diagnosis of Alzheimer’s Disease.
A medical device company with a product pipeline of optical energy therapies for multiple clinical applications.
OmniLife (formerly HealthTech Solutions) >>
OmniLife is Health-IT SaaS c-corporation, initially serving Organ Transplant Centers and Organ Procurement Organizations, that has developed a secure mobile messaging and workflow app that simplifies clinician-to-clinician communication.
Platelet BioGenesis >>
Platelet BioGenesis is a Harvard University spinout that is making human platelets from stem cells.
Pyramid Biosciences >>
Pyramid Bio is dedicated to discovering and developing targeted therapeutics for a wide range of disorders that are regulated by the TRK family.
Quantum Dental >>
QDT has developed a new platform which uses a low-powered laser to detect tooth decay earlier & more accurately than traditional caries detection technologies.
Quthero is committed to disrupting the ways we manage wounds today – from passive ‘dressing’ of wounds to active, rapid, healthy healing with minimal scarring.
RedDress, a private medical device company, has developed a ground breaking, biologic advanced wound care product, based on a patented technology to reproduce the natural process of the body to heal wounds.
Respiratory Motion >>
Respiratory Motion is a medical device company focusing on the development and commercialization of innovative devices to monitor respiratory variation.
RetroSense Therapeutics was founded in 2009 to develop a novel gene therapy approach to vision restoration.
RevBio (formerly LaunchPad Medical) >>
RevBio was started with one goal in mind—to end medicine’s 50 year search for a biocompatible bone adhesive. Effective for bone-to-bone as well as bone-to-metal wet field applications, Tetranite® is a revolutionary biomaterial that promises to transform bone repair—for both patients and clinicians.
Siamab Therapeutics (formerlly Sialix) >>
Developing therapeutic antibodies targeting glycan alterations present in the majority of solid tumors — including colorectal, lung, ovarian, breast, prostate, and pancreatic cancer.
Siva Therapeutics >>
Siva Therapeutics is developing an elegant, safe and effective cancer treatment termed Targeted Hyperthermia™ (THT), which generates therapeutic heat within solid tumors using SivaRods™ gold nanorods and a SivaLum™ infrared light device.
Skyline Medical (formerly BioDrain Medical, Inc.) >>
Skyline Medical has a fully automated, patented, and FDA cleared surgical fluid disposal device—the STREAMWAY System—that virtually eliminates operating room workers’ exposure to blood, irrigation fluid and other potentially infectious fluids found in the surgical environment.
Developing SmartInsulin™, the first glucose-regulated, subcutaneously injectable insulin formulation for treating diabetes.
Spring Loaded Technology >>
Spring Loaded is designing the world’s first bionic knee bracing technology to enhance the strength and power of the leg muscles.
Tetragenetics has developed Tetrahymena, a unique, game changing, disruptive technology to advance drug development.
TruTouch has developed, produced, and is selling a touch-based noninvasive alcohol concentration measurement system that is user friendly, instantaneous and cost effective.
Develops advanced wireless biosensor technologies for on-patient monitoring and management of chronic illnesses.
Developed DermaLOC™, an innovative and disruptive wound closure device.
Windgap Medical >>
Windgap Medical is developing healthcare products that meet the demands of your lifestyle.
Winter Innovations >>
Winter Innovations is a medical device startup developing simple tools for overlooked areas in orthopedic surgery to improve patient outcomes.
Xeno Biosciences >>
Xeno is a biopharmaceutical company pioneering a novel class of therapeutics to address large unmet needs in metabolic disease.
Xylyx Bio >>
Xylyx is implementing a new vision for how advanced biological systems can yield insights that improve patient health and quality of life.
ZetrOZ Systems is the global leader in non-invasive medical devices to accelerate tissue healing and relieve pain for chronic musculoskeletal conditions.
Zylö Therapeutics >>
Many products have limited duration-of-effect, requiring constant re-application. Zylö Therapeutics Patchless Patch solves this, providing a clear-cut marketing advantage.
1908 Brands >>
1908 Brands managers 6 brands to leverage sales and marketing expertise, while reducing expenses per brand.
Aircuity provides sensing and ventilation control solutions for commercial buildings that cost-effectively reduce building energy costs by 20% to 40% without sacrificing occupant comfort, health or productivity.
Connecting patrons with restaurants One Meal Deal at a time.
Alva Systems was founded in 2010 to bring its LED lighting system intellectual property to the >$75B global lighting market.
Amuse Technologies >>
Amuse activates archives and exhibitions by placing their stories in the real world.
Archer Roose Wines >>
Archer Roose Wines is a modern wine brand that unites world class winemaking and transparency in sustainable packaging (cans and kegs!) for the lifestyle of the modern consumer.
Athletic Standard >>
Athletic Standard provides a proven rating system to identify athletic ability and potential for students, coaches and the sports industry.
BoardOnTrack provides charter schools with an online governance platform and unmatched expert guidance.
BrandVerge is a marketplace + workflow tool for premium marketing programs.
Candidly (formerly FutureFuel.io) >>
Candidly is a fully configurable financial wellness platform that addresses the full lifecycle of education expenses.
Chasma Interactive Publishing
Publisher of interactive entertainment applications for wireless devices.
Distributor of plastic containers and related products.
CleanFiber (formerly UltraCell Insulation) >>
CleanFiber LLC makes high performance building insulation from recycled corrugated cardboard, using a patented and proven process.
ConveyIQ (formerly Take The Interview, Inc.) >>
ConveyIQ is a cloud-based video interviewing platform for employers and job candidates.
CoolChip is commercializing an innovative air-moving paradigm for electronics cooling.
DetraPel manufactures non-toxic, PFAS-free, superhydrophobic liquid repellents that utilizes nanotechnology to block and repel any stains on any surface.
EcoSoul Home Inc. >>
At EcoSoul, we’re on a mission to accelerate the world’s transition to a sustainable lifestyle by creating eco-friendly goods for all from Earth’s most renewable resources. Founded in Boston, we’ve expanded our operations across the globe, with our supply chain spanning across India, China and Vietnam.
Emerginvest will make the difficult process of investing in stocks in Emerging Markets much easier.
Finale Dessert Company
Operator of upscale dessert restaurants
Fynalist is an exclusive, invite-only platform for corporate recruiters.
Green Piñata Toy Share >>
Green Piñata Toy Share delivers safe, educational toys right to your door.
Grocery marketers waste billions of dollars a year reaching the wrong shoppers. We target the right shoppers and we only charge for success.
Developer and manufacturer of digital audio amplifier integrated circuits with improved power efficiency and superior audio quality for the consumer electronics marketplace.
Julianna Rae >>
Using the highest quality eco-friendly fabrics including the finest silks, high threadcount cottons and modern micromodal, Julianna Rae makes clothes and intimate apparel to meet the fit and fashion needs of today’s woman and today’s eco-conscious buyer.
KnipBio is developing an ultra-high yield fermentation process with unique growth characteristics to address tightening supplies of fish meal and other nutritional gaps in formulated feeds.
LUMO’s vision is to be the leading technology company that designs products to enhance the lives of the pets we love!
Motus Games Corp. (formerly Fortescue Corporation)
Motus Games is helping define the future of motion-based entertainment.
Pixability helps business do online video marketing.
PlaceMe helps companies with entry- to mid-level talent attraction and retention by providing convenient & accessible housing.
Plymouth Holdings will pursue substantial investment opportunities in the current real estate market through development of one or more Real Estate Investment Trusts.
The company provides prenatal supplement drink mixes that provide the full spectrum of vitamins required for expectant mothers and their unborn child and that soothe symptoms of morning sickness and minimize iron induced constipation.
Scoopfree (formerly Lucky Litter)
Develops and sells innovative pet products that allow pet lovers to spend less time on unpleasant pet care chores so they can spend more quality time with their pets.
Developed a wireless sensor and remote monitoring service, enabling restaurants to efficiently monitor their grease interceptor via the web.
Simple Science >>
Simple Science Hypochlorous technology helps people lead healthier lives through healthier products, like our antimicrobial skin therapies that contain no steroids or our household cleaners that contain no harmful chemicals.
Testive combines technology with human coaches to keep your college-bound kid on track and ready to conquer the ACT or SAT.
A web community that unleashes the imagination of any child by empowering them to write, illustrate, co-author, share, and publish their own books (acquired by Barnes&Noble in 2009).
Zoom Systems (formerly VIGIX) >>
Develops small kiosks that provide entertainment content to the spontaneous consumer through a quick and delightful experience.
Chariot Payments (formerly Tunnel) >>
Chariot utilizes a proprietary DLT (Distributed Ledger Technology) to bring global payments into the 21st Century to properly serve today’s ultra-scalable, globally-connected business and individuals on today’s fiat and DeFi platforms.
EarthGrid’s vision is to build a subterranean network of tunnels to rapidly eliminate fossil fuels, reach 100% renewable energy, and offer quantum ultra-high-speed Internet, sustainable clean water, wastewater, transportation & delivery services..
Harmony Line, Inc., located in Cambridge, Massachusetts, commercializes music technologies that unlock the expressive musician and composer in everyone.
Developed an energy and environmentally efficient combustion-based process technology
NextShift Robotics helps online retailers expedite order fulfillment with autonomous warehouse robots. NSR machines provide the scalability required to keep pace with increasing demand and ever rising customer expectations.
Sifaka is the premier wildlife-themed site in the rapidly growing virtual world market, with early comparisons to Club Penguin
Develops extremely reliable, safe and reusable systems for low-cost spaceflight.
3Derm – M&A
Aras – M&A
Carbonite – IPO
Corbus Pharmaceuticals – IPO
Horizontal – M&A
Medumo – M&A
Neuraly – M&A
NextShift Robotics – M&A
RetroSense Therapeutics – M&A
Siamab Therapeutics – M&A
SmartCells – M&A
TetraGenetics – M&A