15Dec
04Dec
CT Biotech Firm Working Drug to Treat Stroke, Brain Injuries
Co-founded by William Korinek of Stonington, who spent nearly a decade at Pfizer, Astrocyte Pharmaceuticals expects to launch a phase one clinical trial of its leading drug candidate in the first half of 2022. Last week, Astrocyte put out word that Stroke, a peer-reviewed journal, had published the results of preclinical studies of the drug, known for now as AST-004. The lack of available treatments for stroke is a major unmet medical need, one that could qualify Astrocyte’s drug development...
02Dec
Groton biotech firm working on much-needed drug to treat stroke, brain injuries
A small drug development company that moved its headquarters from Cambridge, Mass., to the BioCT Innovations Commons on Shennecossett Road last year is aiming to have a huge impact on the treatment of strokes and brain injuries. Co-founded by William Korinek of Stonington, who spent nearly a decade at Pfizer, Astrocyte Pharmaceuticals expects to launch a phase one clinical trial of its leading drug candidate in the first half of 2022. Read more >>
23Nov
Astrocyte Pharmaceuticals Announces Publication in the Journal Stroke of Results Supporting Advancement of AST-004 into in the Clinic
Astrocyte Pharmaceuticals Inc., a drug discovery and development company advancing novel neuroprotective therapeutics for the treatment of brain injuries, today announced the publication of a manuscript in the peer reviewed journal Stroke entitled: Adenosine A1R/A3R (Adenosine A1 and A3 Receptor) Agonist AST-004 Reduces Brain Infarction in a Nonhuman Primate Model of Stroke. The manuscript describes the results of pre-clinical studies using AST-004, Astrocyte’s lead drug candidate, for the treatment of stroke. Read more >>
19Oct
San Antonio researchers developing brain injury treatment
Research that began in San Antonio could soon produce a first-of-its-kind treatment for traumatic brain injuries, like concussions and strokes. The drug, which scientists hope to eventually administer as a pill, stimulates support cells responsible for cleaning up messes in the brain. These "astrocytes" are responsible for maintaining the environment in which nerve cells operate. "We found a mechanism with which you could increase the energy production of an astrocyte," said Dr. Jim Lechleiter, professor of cell systems and anatomy...
05Oct
Brain injury therapy advancing toward human studies
Research that began at The University of Texas Health Science Center at San Antonio 15 years ago is nearing a significant milestone: human testing of an intravenous (IV) drug to treat brain injuries such as concussion and stroke. The implications are enormous. A therapy for soldiers on the battlefield, car crash victims, concussed football players and people who suffer strokes could ease the pain and suffering of thousands worldwide daily and prevent debilitating long-term effects of traumatic brain injury. Astrocyte Pharmaceuticals is...
17Sep
MTEC Awards $3M to Astrocyte Pharmaceuticals for Clinical Study of AST-004
Astrocyte Pharmaceuticals Inc., a drug discovery and development company advancing novel neuroprotective therapeutics for the treatment of neurodegenerative brain injuries, announced today the granting of a $3.0M award from the Medical Technology Enterprise Consortium (MTEC). Read more >>
08Sep
Astrocyte Pharmaceuticals Awarded Major Grant to Further Develop Promising Treatment for Brain Injury
Astrocyte Pharmaceuticals Inc., a drug discovery and development company advancing novel neuroprotective therapeutics for the treatment of brain injuries, announced today that it has received a $500,000 award jointly funded by the Medical Technology Enterprise Consortium (MTEC) and the BrightFocus Foundation. Read more >>
13Jun
Neuroprotection Drugs Market is Expected to Reach US$ 33,481.7 Million by 2027 with major key players
Rising usage of atypical antipsychotics, omega‐3 fatty acids, antidepressants, glutamateric neurotransmission modulators, erythropoietin, COX‐2 inhibitors and N‐acetylcysteine have anti‐apoptotic properties which can help in brain maturational processes from psychotic disorders. Clinical trial processes suggested that these category of drugs help in preventing the onset of frank psychosis. A company named, Astrocyte Pharmaceuticals Inc., which is a drug development company is engaged in providing advanced breakthroughs in neuroprotection drugs market to repair neurons that are caused due to brain injury.
30Dec